ヒドロキシメチルグルタリルCoAレダクターゼ (NADPH)（hydroxymethylglutaryl-CoA reductase (NADPH)）は、次の化学反応を触媒する酸化還元酵素である。反応式の通り、この酵素の基質は(R)-メバロン酸とCoAとNADP、生成物は(S)-3-ヒドロキシ-3-メチルグルタリルCoAとNADPHとHである。組織名は(R)-mevalonate:NADP oxidoreductase (CoA-acylating)で、別名にhydroxymethylglutaryl coenzyme A reductase (reduced nicotinamideadenine dinucleotide phosphate), 3-hydroxy-3-methylglutaryl-CoA reductase, β-hydroxy-beta-methylglutaryl coenzyme A reductase, hydroxymethylglutaryl CoA reductase (NADPH), S-3-hydroxy-3-methylglutaryl-CoA reductase, NADPH-hydroxymethylglutaryl-CoA reductase, HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating-CoA), 3-hydroxy-3-methylglutaryl CoA reductase (NADPH), hydroxymethylglutaryl-CoA reductase (NADPH)がある。

出典:wikipedia